Leukocyte common antigen (CD45) negative follicular lymphoma, a rare immunophenotypic presentation

Loss of CD45 expression has been reported, but all cases documented were large B cell lymphoma (LBCL). To the best of our knowledge, this is the first case of low grade follicular lymphoma with lack of CD45 expression. We report this case because of not only its rarity but also to raise awareness that loss of CD45 expression can occur in LBCL as well as in low grade B-cell lymphomas.