Novel antilithiatic cationic proteins from human calcium oxalate renal stone matrix identified by MALDI-TOF-MS endowed with cytoprotective potential: An insight into the molecular mechanism of urolithiasis

► Exploring antilithiatic cationic proteins present in human CaOx stones ► Examine their molecular interactions with COM crystals in silico ► Histone-lysine N-methyltransferase as novel antilithiatic cationic protein ► Inward rectifier K channel as novel antilithiatic cationic protein ► Protein Wnt-2 as novel antilithiatic cationic protein