Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients

► MMP9 R668Q polymorphism is closely associated with LVD in CAD patients. ► MMP9 R668Q may be evaluated as a biomarker for the prediction of LVD in CAD patients ► Present findings may further aid in understanding the pathobiology of heart failure.