On the path to evidence-based reporting of serum protein electrophoresis patterns in the absence of a discernible monoclonal protein - A critical review of literature and practice suggestions

- In the absence of M-protein, reporting SPE patterns and implied conditions is controversial.
- Previous Canada-wide survey showed significant variations in reporting practices.
- Review of evidence supported only some of these reporting practices.
- Ten practice suggestions were made and rationale discussed in light of available evidence.