Aluminum, copper, iron and zinc differentially alter amyloid-Aβ1-42 aggregation and toxicity

► Al, Cu, Fe and Zn differently influence Aβ aggregation. ► Al and Fe induce the formation of fibrillar oligomers of Aβ⋅ ► Only Aβ-Al determines an increased production of tau181 and AβPP in cell culture.