کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8332508 | 1540248 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation and cytotoxicity of N,N,N-trimethyl chitosan/alginate beads containing gold nanoparticles
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Preparation and cytotoxicity of N,N,N-trimethyl chitosan/alginate beads containing gold nanoparticles Preparation and cytotoxicity of N,N,N-trimethyl chitosan/alginate beads containing gold nanoparticles](/preview/png/8332508.png)
چکیده انگلیسی
Polyelectrolyte complex beads based on N,N,N-trimethyl chitosan (TMC) and sodium alginate (ALG) were obtained. This biomaterial was characterised by FTIR, TGA/DTG, DSC and SEM analysis. The good properties of polyelectrolyte complex hydrogel beads were associated, for the first time, with gold nanoparticles (AuNPs). Through a straightforward methodology, AuNPs were encapsulated into the beads. The in vitro cytotoxicity assays on the Caco-2 colon cancer cells and healthy VERO cells showed that the beads presented good biocompatibility on both cell lines, whereas the beads loaded with gold nanoparticles (beads/AuNPs) was slightly cytotoxic on the Caco-2 and VERO cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 72, January 2015, Pages 466-471
Journal: International Journal of Biological Macromolecules - Volume 72, January 2015, Pages 466-471
نویسندگان
Alessandro F. Martins, Suelen P. Facchi, Johny P. Monteiro, Samara R. Nocchi, Cleiser T.P. Silva, Celso V. Nakamura, Emerson M. Girotto, Adley F. Rubira, Edvani C. Muniz,