کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8344658 | 1541586 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lowering of blood pressure after nitrate-rich vegetable consumption is abolished with the co-ingestion of thiocyanate-rich vegetables in healthy normotensive males
ترجمه فارسی عنوان
کاهش فشار خون پس از مصرف سبزیجات غنی از نیتروژن با مصرف سبزیجات غنی از تیتانیوم در مردان سالم رنج می برد
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
A diet rich in vegetables is known to provide cardioprotection. However, it is unclear how the consumption of different vegetables might interact to influence vascular health. This study tested the hypothesis that nitrate-rich vegetable consumption would lower systolic blood pressure but that this effect would be abolished when nitrate-rich and thiocyanate-rich vegetables are co-ingested. On four separate occasions, and in a randomized cross-over design, eleven healthy males reported to the laboratory and consumed a 750â¯mL vegetable smoothie that was either: low in nitrate (â¼0.3â¯mmol) and thiocyanate (â¼5â¯Î¼mol), low in nitrate and high in thiocyanate (â¼72â¯Î¼mol), high in nitrate (â¼4â¯mmol) and low in thiocyanate and high in nitrate and thiocyanate. Blood pressure as well as plasma and salivary [thiocyanate], [nitrate] and [nitrite] were assessed before and 3â¯h after smoothie consumption. Plasma [nitrate] and [nitrite] and salivary [nitrate] were not different after consuming the two high-nitrate smoothies, but salivary [nitrite] was higher after consuming the high-nitrate low-thiocyanate smoothie (1183â¯Â±â¯625â¯Î¼M) compared to the high-nitrate high-thiocyanate smoothie (941â¯Â±â¯532â¯Î¼M; Pâ¯<â¯.001). Systolic blood pressure was only lowered after consuming the high-nitrate low-thiocyanate smoothie (â3â¯Â±â¯5â¯mmHg; Pâ¯<â¯.05). The acute consumption of vegetables high in nitrate and low in thiocyanate lowered systolic blood pressure. However, when the same dose of nitrate-rich vegetables was co-ingested with thiocyanate-rich vegetables the increase in salivary [nitrite] was smaller and systolic blood pressure was not lowered. These findings might have implications for optimising dietary guidelines aimed at improving cardiovascular health.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nitric Oxide - Volume 74, 1 April 2018, Pages 39-46
Journal: Nitric Oxide - Volume 74, 1 April 2018, Pages 39-46
نویسندگان
Rebecca Dewhurst-Trigg, Toby Yeates, Jamie R. Blackwell, Christopher Thompson, Adam Linoby, Paul T. Morgan, Ida Clarke, Luke J. Connolly, Lee J. Wylie, Paul G. Winyard, Andrew M. Jones, Stephen J. Bailey,