کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8344683 1541587 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of diet and gut environment on the gastrointestinal formation of N-nitroso compounds: A review
ترجمه فارسی عنوان
تأثیر رژیم غذایی و محیط روده بر شکل گیری ترکیبات نیتروزو دستگاه گوارش: یک بررسی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی
Diet is associated with the development of cancer in the gastrointestinal (GI) tract, because dietary nitrate and nitrite are the main nitrosating agents that are responsible for the formation of carcinogenic N-nitroso compounds (NOCs) when nitrosatable substrates, such as amine and amide, are present in the GI tract. However, whether the nitroso compounds become beneficial S-nitroso compounds or carcinogenic NOCs might depend on dietary and environmental factors including food stuffs, gastric acidity, microbial flora, and the mean transit time of digesta. This review focused on GI NOC formation and environmental risk factors affecting its formation to provide appropriate nutritional strategies to prevent the development of GI cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nitric Oxide - Volume 73, 28 February 2018, Pages 66-73
نویسندگان
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