کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8350866 | 1541857 | 2014 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Corticosterone and propranolol's role on taste recognition memory
ترجمه فارسی عنوان
نقش کورتیکواسترون و پروپرانولول در حافظه تشخیص طعم
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کلمات کلیدی
کورتیکواسترون، پروپرانولول، حافظه، عطر و طعم، تست تشخیص طعم، موش
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
Taste recognition is a robust procedure to study learning and memory processes, as well as the different stages involved in them, i.e. encoding, storage and recall. Considerable evidence indicates that adrenal hormones and the noradrenergic system play an important role in aversive and appetitive memory formation in rats and humans. The present experiments were designed to characterize the effects of immediate post training corticosterone (Experiment 1) and propranolol administration (Experiment 2 and 3) on taste recognition memory. Administration of a high dose of corticosterone (5Â mg/kg, sc) impairs consolidation of taste memory, but the low and moderate doses (1 and 3Â mg/kg, sc) didn't affect it. On the other hand, immediate post-training administration of propranolol (1 and 2Â mg/kg, ip) impaired taste recognition memory. These effects were time-dependent since no effects were seen when drug administration was delayed 3Â h after training. These findings support the importance of stress hormones and noradrenergic system on the modulation of taste memory consolidation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 127, December 2014, Pages 37-41
Journal: Pharmacology Biochemistry and Behavior - Volume 127, December 2014, Pages 37-41
نویسندگان
E. Ruetti, N. Justel, A. Mustaca, M. Boccia,