Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism

► Ropinirole improved movement impairment in MPTP-treated mice. ► Ropinriole protected dopaminiergic neurons. ► Ropinirole has neuroprotective effects by inhibiting mitochondria-mediated apoptosis.