Glucagon-like peptide-1(1-37) can enhance blood glucose homeostasis in mice

► GLP-1(1-37) can lower blood glucose levels both in normal and diabetic mice. ► GLP-1(1-37) is a highly potent agonist of the GLP-1 receptor. ► The glucose-lowering effect of GLP-1(1-37) could not be blocked by exendin(9-39). ► GLP-1(1-37) is more stable than GLP-1(7-37) in mouse serum.