کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8405593 | 1544897 | 2018 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anticoagulation, fibrinolytic and the cytotoxic activities of sulfated hemicellulose extracted from rice straw and husk
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Anticoagulation, fibrinolytic and the cytotoxic activities of sulfated hemicellulose extracted from rice straw and husk Anticoagulation, fibrinolytic and the cytotoxic activities of sulfated hemicellulose extracted from rice straw and husk](/preview/png/8405593.png)
چکیده انگلیسی
Rice straw and husk are one of the major agricultural wastes in Egypt, which cause problems for farmers. Hemicellulose is considered one of the major components of straw and husk lignocellulosic biomass. The new methods and techniques for hemicellulose extraction from renewable with low cost and their modification to produce a promising value-added hemicellulose derivative are important issues. Therefore, the present study aimed at extracting hemicellulose from Egyptian agriculture wastes rice straw and husk by 4% sodium hydroxide at 90â¯Â°C. The extracted hemicellulose was purified by 5% hydrogen peroxide and separated into soluble and insoluble hemicellulose in distilled water. The sulfation process of hemicellulose was done in presence of two different catalysts (N, N-Dicyclohexylcarbodiimide (DCC) and 4-Dimethylaminopyridine (DMAP)). Results showed that the sulfated soluble hemicelluloses have the highest degree of sulfation (DS) with low total carbohydrate content. The prepared sulfated hemicellulose using DCC or DMAP showed promising biological activities such as anticoagulation activity at 31.25â¯Âµg/mL and fibrinolytic activity lysis more than 80% at 2000â¯Âµg/mL compared standard (Hemoclar). These sulfated hemicellulose compounds were practically non-toxic on the VERO cells with LD50 â¥â¯5000â¯mg /Kg.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biocatalysis and Agricultural Biotechnology - Volume 15, July 2018, Pages 86-91
Journal: Biocatalysis and Agricultural Biotechnology - Volume 15, July 2018, Pages 86-91
نویسندگان
Tamer I.M. Ragab, Hassan Amer, Abdel Tawab Mossa, Mahmoud Emam, A.A. Hasaballah, Wafaa A. Helmy,