کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8455782 1548329 2014 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of gene expression changes in A549 cells induced by organic compounds from respirable air particles
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Analysis of gene expression changes in A549 cells induced by organic compounds from respirable air particles
چکیده انگلیسی
In conclusion, numerous processes and pathways deregulated in response to EOMs suggest a significant role of activated AhR. Interestingly, we did not observe substantial gene expression changes related to DNA damage response, possibly due to the antagonistic effect of non-genotoxic EOM components. Moreover, a comparison of EOM effects with other available data on modulation of global gene expression suggests possible overlap among the effects of PM2.5, EOMs and various types of AhR agonists.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 770, December 2014, Pages 94-105
نویسندگان
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