Adjuvant effects of poly I:C and imiquimod on the immunization of kuruma shrimp (Marsupenaeus japonicus) with a recombinant protein, VP28 against white spot syndrome virus

Major contributors to economic losses in shrimp aquaculture are viral diseases, of which white spot syndrome virus (WSSV) is the most important one due to its rapid spread and economic impact. In this paper, we present an immunization method towards prevention of WSSV disease in kuruma shrimp using adjuvants such as poly I:C or imiquimod along with a sub-unit protein (rVP28).