کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8497772 1553549 2018 28 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Invertebrate host responses to microsporidia infections
ترجمه فارسی عنوان
پاسخ میزبان بی مهره به عفونت های میکروسپوریدیایی
کلمات کلیدی
میکروسپوریدیا، بی مهره، پاسخ میزبان، ایمنی فزاینده، حشره،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
چکیده انگلیسی
Microsporidia are a group of fungi-like intracellular and unicellular parasites, which infect nearly all animals. As “master parasites”, over 1400 microsporidian species have been described to date. Microsporidia infections in economical invertebrates (e.g., silkworm, shrimp) cause huge financial losses, while other microsporidia infections in daphnia, nematode, locust, honeybee and mosquito play important roles in the regulation of their population size. Research investigating invertebrate host responses following microsporidia infections has yielded numerous interesting results, especially pertaining to the innate immune response to these pathogens. In this review, we comparatively summarize the invertebrate host responses to various microsporidia infections. We discuss numerous critical events in host responses including ubiquitin-mediated resistance, production of reactive oxygen species, melanization and innate immune pathways, and the increased basic metabolism and the accumulation of juvenile hormone in infected hosts. Recent studies progressing our understanding of microsporidia infection are also highlighted. Collectively, these advances shed more light on general rules of invertebrate host immune responses and pathogenesis mechanisms of microsporidia, and concurrently offer valuable clues for further research on the crosstalk between hosts and intracellular pathogens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 83, June 2018, Pages 104-113
نویسندگان
, , , , , , , ,