Chinese herbal medicine compound Yi-Zhi-Hao pellet inhibits replication of influenza virus infection through activation of heme oxygenase-1

The Chinese herbal medicine, compound Yi-Zhi-Hao pellet had a broad-spectrum anti-influenza activity in vitro, including clinically drug-resistant strains. It protected influenza A virus-infected cells from oxidative damages, at least partly by activating expression of Nrf2/HO-1 pathway.230