New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis

New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical Pharmacology - Volume 154, August 2018, Pages 255-264

Qian-Ting Tian, Chun-Yong Ding, Shan-Shan Song, Ying-Qing Wang, Ao Zhang, Ze-Hong Miao,