کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8551256 1562107 2018 44 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Exposure to beta-cypermethrin impairs the reproductive function of female mice
ترجمه فارسی عنوان
قرار گرفتن در معرض بتا-سایپرمترین باعث کاهش عملکرد تولید مثل موش ماده می شود
کلمات کلیدی
بتایپرمترین، عملکرد تولید مثل زنانه، موش،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
This study aimed to investigate the effects of beta-cypermethrin (β-CYP) on female reproductive function and examine the morphology of the uterine endometrium and follicular development. The results found that the rate of successful pregnancy in the β-CYP-treated groups significantly decreased. The levels of serum E2 and FSH were significantly increased in the β-CYP-treated groups. The concentrations of serum P and LH were significantly decreased in the β-CYP-treated groups. The uterine endometrium was damaged and the endometrial pinopode was markedly inhibited. In addition, the total number of follicles of all types was significantly lower in the medium- and high-dose β-CYP-treated groups. These results suggest that β-CYP significantly affected the reproductive function of female mice. β-CYP may have significantly decreased the fertility of female mice by disturbing the reproductive hormone concentrations and inhibiting the development of the endometrium and the endometrial pinopode.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 95, June 2018, Pages 385-394
نویسندگان
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