کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8553777 | 1562694 | 2018 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Safety evaluation of the temporary consolidant based on a zebrafish embryo model
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Safety evaluation of the temporary consolidant based on a zebrafish embryo model Safety evaluation of the temporary consolidant based on a zebrafish embryo model](/preview/png/8553777.png)
چکیده انگلیسی
It was shown that embryo exposure to temporary consolidants resulted in an increased mortality and malformation rate, and a decreased hatching rate. The order of embryo toxicity of the four types of temporary consolidants tested was mentholâ¯>â¯coumarinâ¯>â¯ethyl maltolâ¯>â¯cyclododecane. Although the embryo toxicity of cyclododecane was minimal, some studies have indicated that this temporary consolidant could be bioaccumulated. The results also suggested that the zebrafish embryos can serve as a reliable model for the evaluation of embryo toxicity of temporary consolidants, as this model could offer the possibility to perform the rapid, medium throughput, cost-effective analyses.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology in Vitro - Volume 51, September 2018, Pages 50-53
Journal: Toxicology in Vitro - Volume 51, September 2018, Pages 50-53
نویسندگان
Lu Zhang, Xiao Yan Zhang, Yulan Hu, Bing Jian Zhang,