کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8625222 | 1568112 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fat mass is positively associated with bone mass acquisition in children with small or normal lean mass: A three-year follow-up study
ترجمه فارسی عنوان
توده چربی به طور مثبت با استخراج توده استخوانی در کودکان با توده کوچک و یا نرمال همراه است: یک مطالعه پیگیری سه ساله
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کلمات کلیدی
BMCDXAaBMDLSTMAdipocytes - آدیپوسیتAreal bone mineral density - تراکم معدنی استخوان منطقهfat mass - توده چربیdual-energy X-ray absorptiometry - جذب اندازه گیری اشعه ایکس دوگانه انرژیGeneral population - جمعیت عمومیDensitometry - دانسیومتریbody mass index - شاخص توده بدنBMI - شاخص توده بدنیFat mass index - شاخص توده چربیFMI - صندوق بین المللی پولBone mineral content - محتوای مواد معدنی استخوانChild - کودک
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
چکیده انگلیسی
The independent impact of fat mass (FM) on bone health is difficult to assess, as FM is correlated with lean soft tissue mass (LSTM). In a previous cross-sectional study, FM was suggested to help promote high bone mass acquisition in adolescents with small LSTM. The present prospective cohort study investigated the effects of FM on bone in pubertal children after stratification by height-normalized index of LSTM (LSTMI). The source population was all 5th grade children enrolled in either one of the two public elementary schools in Hamamatsu, Japan. Of these, 545 children who participated in both baseline (at age 11) and follow-up (at age 14) surveys were included in the present analysis. Body composition and whole body areal bone mineral density (aBMD) were measured using dual-energy X-ray absorptiometry. From baseline to follow-up, significant (PÂ <Â 0.05) differences were observed in changes in aBMD among tertiles of change in FM in both sexes after adjusting for confounding factors including LSTMI. After stratification by tertiles of sex-specific LSTMI, adjusted means of changes in aBMD according to tertiles of change in FM within the lowest and second lowest tertiles of LSTMI in both sexes showed a significant increase from the lower tertiles to the highest tertile of change in FM. In the highest tertile of LSTMI, changes in FM showed no significant association with changes in aBMD. These findings suggest that adipose tissue might help promote high bone mass acquisition in pubertal children with small or normal LSTMI.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 107, February 2018, Pages 222-227
Journal: Bone - Volume 107, February 2018, Pages 222-227
نویسندگان
Katsuyasu Kouda, Kumiko Ohara, Harunobu Nakamura, Yuki Fujita, Myadagmaa Jaalkhorol, Masayuki Iki,