کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8681644 1579650 2018 29 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Management of leptomeningeal metastasis in breast cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Management of leptomeningeal metastasis in breast cancer
چکیده انگلیسی
Leptomeningeal metastasis (LM), which occurs when malignant cells spread to the central nervous system, is becoming an increasingly common complication in patients with breast cancer. Diagnosis and treatment of LM is challenging. Moreover, prognosis of patients with LM is poor, with a median survival of 6 months after diagnosis. This review highlights the strengths and limitations of currently available diagnostic tools and therapies for LM. The current treatments for LM, including radiotherapy, systemic therapy, and intrathecal treatment, aim to maintain the quality of life of patients by correcting neurological deficits and arresting neurological degeneration. However, there is no standardized therapy for LM because of a lack of randomized trials on this condition.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurology and Neurosurgery - Volume 172, September 2018, Pages 151-159
نویسندگان
, , , ,