کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
868316 909806 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation of mixed-templates molecularly imprinted polymers and investigation of the recognition ability for tetracycline antibiotics
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Preparation of mixed-templates molecularly imprinted polymers and investigation of the recognition ability for tetracycline antibiotics
چکیده انگلیسی

We developed in the present study a set of molecularly imprinted polymers (MIPs) by precipitation polymerization, using four members of tetracycline antibiotics (TCs) as templates (Oxytetracycline, Tetracycline, Chlortetracycline and Doxycycline). Then, based on the imprinting effect of different MIPs (TCs), Oxytetracycline and Chlortetracycline were chosen as mixed-templates to synthesize high selective MIPs for recognition of a family of analytes. And the characterization of obtained MIPs was analyzed by FESEM analysis, Brunauer–Emmett–Teller (BET) method, polymer size analysis, and determination of swelling ratio and COOH capacity. It was shown that the optimal imprinting factors of TCs on mixed-templates MIPs were more than 6.0 and the maximum binding amount of TCs were about 27 μmol g−1 (Oxytetracycline), 35 μmol g−1 (Tetracycline), 35 μmol g−1 (Chlortetracycline) and 39 μmol g−1 (Doxycycline), respectively. Finally, the mixed-templates MIPs were shown to be promising for on-line solid-phase extraction-HPLC-UV determination of trace TCs in foodstuffs. With a sample loading volume of 10 mL, the enhancement factors were in the range of 159–410.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 25, Issue 10, 15 June 2010, Pages 2218–2224
نویسندگان
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