Microstructural white matter changes and their relation to neuropsychological deficits in patients with juvenile myoclonic epilepsy

The present study results showed neuropsychological deficits including frontal lobe cognitive performance and a tendency toward alexithymia as well as accompanying microstructural neuroimaging changes in patients with JME, which all point to alterations in frontal brain regions and frontal thalamocortical networks in these patients.