کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8684576 1580131 2018 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optogenetic exploration and modulation of pain processing
ترجمه فارسی عنوان
اکتشاف اپی تگنیتیک و مدولاسیون پردازش درد
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی
Intractable pain is the single most common cause of disability, affecting more than 20% of the population world-wide. There is accordingly a global effort to decipher how changes in nociceptive processing in the peripheral and central nervous systems contribute to the onset and maintenance of chronic pain. The past several years have brought rapid progress in the adaptation of optogenetic approaches to study and manipulate the activity of sensory afferents and spinal cord neurons in freely behaving animals, and to investigate cortical processing and modulation of pain responses. This review discusses methodological advances that underlie this recent progress, and discusses practical considerations for the optogenetic modulation of nociceptive sensory processing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Neurology - Volume 306, August 2018, Pages 117-121
نویسندگان
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