AAV-mediated netrin-1 overexpression increases peri-infarct blood vessel density and improves motor function recovery after experimental stroke

► AAV mediated netrin-1 gene transfer improves post stroke motor function recovery. ► AAV-Netrin-1 gene transfer enhances peri-infarct blood vessel density. ► AAV-Netrin-1 gene transfer increases neuroblast migration. ► Sustained netrin-1 overexpression via AAV gene transfer is beneficial after stroke.