کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8720628 | 1589307 | 2018 | 35 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Surgery in ulcerative colitis: When? How?
ترجمه فارسی عنوان
جراحی در کولیت زخمی: وقتی؟ چطور؟
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کلمات کلیدی
بیماری روده التهابی داروها، عمل جراحی، زمان سنجی، کولیت زخم، مدیریت چند جانبه،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی
Approximately 15% of UC patients develop an acute attack of severe colitis, and 30% of these patients require colectomy. The initial treatment strategy in UC typically follows the traditional step-up approach. One third of the patients will not respond to steroid therapy and cyclosporine and infliximab are the most common salvage agents employed in these cases in order to avoid emergent surgery. Unfortunately, although a significant short-term benefit have been observed after infliximab treatment, the colectomy rate have remained stable. Surgery in UC depends on the stage of the disease as well as patient's status and is divided into the following settings: urgent, emergent and elective. Despite many efforts the surgical management of UC remains a significant challenge. A multidisciplinary management of UC is key in order to define the best timing and the best procedure for each patient in an individualized basis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Gastroenterology - Volumes 32â33, FebruaryâApril 2018, Pages 71-78
Journal: Best Practice & Research Clinical Gastroenterology - Volumes 32â33, FebruaryâApril 2018, Pages 71-78
نویسندگان
Gaetano Gallo, Paulo Gustavo Kotze, Antonino Spinelli,