کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8732790 | 1590546 | 2017 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Parasitoses intestinais: efeito protetor na artrite reumatoide?
ترجمه فارسی عنوان
انگل روده: اثر محافظتی بر آرتریت روماتوئید دارد؟
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب سالمندان و علم پیری شناسی
چکیده انگلیسی
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, with a progressive course, characterized by chronic synovitis that may evolve with deformities and functional disability, and whose early treatment minimizes joint damage. Its etiopathogenesis is not fully elucidated but comprises immunologic responses mediated by T helper cells (Th1). An apparent minor severity of RA in patients from regions with lower income could be associated with a higher prevalence of gut parasites, especially helminths. Strictly, a shift in the immune response towards the predominance of T helper cells (Th2), due to the chronic exposure to helminths, could modulate negatively the inflammation in RA patients, resulting in lower severity/joint injury. The interaction between the immunological responses of parasitic helminths in rheumatoid arthritis patients is the purpose of this paper.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Brasileira de Reumatologia - Volume 57, Issue 5, SeptemberâOctober 2017, Pages 461-465
Journal: Revista Brasileira de Reumatologia - Volume 57, Issue 5, SeptemberâOctober 2017, Pages 461-465
نویسندگان
Sandra Maximiano de Oliveira, Ana Paula Monteiro Gomides, LÃcia Maria Henrique da Mota, Caliandra Maria Bezerra Luna Lima, Francisco Airton Castro Rocha,