کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8732810 | 1590547 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Policondrite recidivante: prevalência de doenças cardiovasculares e seus fatores de risco e caracterÃsticas gerais da doença de acordo com o gênero
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب سالمندان و علم پیری شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The comorbidities in relapsing polychondritis (RP) have been scarcely described in the literature. Moreover, apart from a few RP epidemiological studies, no studies specifically addressing RP distribution according to gender are available. Therefore, the objetives of the present study were: (a) to analyse the prevalence of cardiovascular diseases and its risk factors in a series of patients with RP; (b) to determine the influence of gender on RP. A crossâsectional tertiary single center study evaluating 30 RP cases from 1990 to 2016 was carried out. To compare comorbidities, 60 healthy individuals matched for ageâ, genderâ, ethnicityâ and body mass index were recruted. The mean age of RP patientes was 49.0 ± 12.4 years, the median disease duration 6.0 years, and 70% were women. A higher frequency of arterial hypertension (53.3% vs. 23.3%; p = 0.008) and diabetes mellitus (16.7% vs. 3.3%; p = 0.039) was found in the RP group, compared to the control group. As an additional analysis, patients were compared according to gender distribution (9 men vs. 21 women). The clinical disease onset features were comparable in both genders. However, over the followâup period, male patients had a greater prevalence of hearing loss, vestibular disorder and uveitis events, and also received more cyclophosphamide therapy (p < 0.05). There was a high prevalence of arterial hypertension and diabetes mellitus, and the male patients seemed to have worse prognosis than the female patients in the follow up.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Brasileira de Reumatologia - Volume 57, Issue 4, JulyâAugust 2017, Pages 338-345
Journal: Revista Brasileira de Reumatologia - Volume 57, Issue 4, JulyâAugust 2017, Pages 338-345
نویسندگان
Pablo Arturo Olivo Pallo, MaurÃcio LevyâNeto, Rosa Maria Rodrigues Pereira, Samuel Katsuyuki Shinjo,