کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8736511 1591143 2017 29 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interleukin-22 in human inflammatory diseases and viral infections
ترجمه فارسی عنوان
اینترلوکین -22 در بیماری های التهابی انسانی و عفونت های ویروسی
کلمات کلیدی
اینترلوکین 22، اینترلوکین 10 خانواده، بیماری التهابی عفونت ویروسی، مولتیپل اسکلروزیس،
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی
Interleukin-22 (IL22) is one of the members of IL10 family. Elevated levels of this cytokine can be seen in diseases caused by T lymphocytes, such as Psoriasis, Rheumatoid arthritis, interstitial lung diseases. IL22 is produced by different cells in both innate and acquired immunities. Different types of T cells are able to produce IL22, but the major IL22-producing T-cell is the TCD4. TH22 cell is a new line of TCD4 cells, which differentiated from naive T cells in the presence of TNFα and IL6; 50% of peripheral blood IL22 is produced by these cells. IL22 has important functions in host defense at mucosal surfaces as well as in tissue repair. In this review, we assess the current understanding of this cytokine and focus on the possible roles of IL-22 in autoimmune diseases.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 16, Issue 12, December 2017, Pages 1209-1218
نویسندگان
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