کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8737186 1591325 2018 23 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of a two-stage testing algorithm for the diagnosis of respiratory viral infections
ترجمه فارسی عنوان
بررسی الگوریتم تست دو مرحله ای برای تشخیص عفونت های ویروسی تنفسی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی
New on-demand multiplex molecular respiratory viral diagnostics offer superior performance although can be expensive and some platforms cannot process multiple specimens simultaneously. We performed a retrospective study reviewing results of patients tested for respiratory viruses following introduction of a two-stage testing algorithm incorporating an initial screen with Sofia® immunoassay then secondary Biofire Filmarray®, and compared to a period when only Filmarray® was used. Of 2976 testing episodes, 1814 underwent initial Sofia® then follow-up FilmArray®. A diagnosis of influenza was made by Sofia® in 282 patients, and by FilmArray® in an additional 163 (median time to result 1.12 hours versus 3.46 hours, P < 0.001). Significantly more patients received their diagnosis within 90 minutes in winter despite testing more samples (11.1% versus 3.4%, P < 0.001), and approximately $36,000 was saved. An algorithmic approach to respiratory viral diagnosis can combine the advantages of accuracy and speed and be cost saving.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 91, Issue 4, August 2018, Pages 319-323
نویسندگان
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