کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8745616 | 1593174 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Long-term stability in the gut microbiome over 46â¯years in the life of Billy Apple®
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
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چکیده انگلیسی
There is currently a lack of long-term longitudinal studies investigating the stability of the microbiome. In this n-of-one study, we characterised the gut microbial composition of artist Billy Apple® from stool samples collected 45â¯years apart in 1970 and 2016. We observed that 45% of the microbial species were retained over the 45â¯year interval. Moreover, components of Apple's microbiome associated with the allele frequency at seven SNPs in his genome. Collectively, our results are consistent with a genetic component contributing to the selection and maintenance of core members within the artist's microbiome over his life-time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Human Microbiome Journal - Volumes 5â6, December 2017, Pages 7-10
Journal: Human Microbiome Journal - Volumes 5â6, December 2017, Pages 7-10
نویسندگان
Thilini N. Jayasinghe, Craig Hilton, Peter Tsai, Billy Apple, Peter Shepherd, Wayne S. Cutfield, Justin M. O'Sullivan,