Inhibition effects of polysaccharides on HBV replication and cell proliferation from Lentinus edodes waste material

- PLWM inhibited the secretion of HBsAg and HBeAg.
- PLWM had no effect on the inhibition of HBV DNA replication, but 50 µg/ml PLWM strengthened the inhibition effect on HBV DNA replications of Lamivudine (10 µmol/l).
- PLWM could inhibit cell proliferation and affect the expression of some anti-apoptosis proteins.