کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
875797 910809 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design of tissue engineering scaffolds based on hyperbolic surfaces: Structural numerical evaluation
ترجمه فارسی عنوان
طراحی سازه های مهندسی بافت بر اساس سطوح هذلولی: ارزیابی عددی ساختاری
کلمات کلیدی
مهندسی بافت، داربست، سطوح هیپربولیک، شبیه سازی عددی، تجزیه و تحلیل ساختاری
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی

Tissue engineering represents a new field aiming at developing biological substitutes to restore, maintain, or improve tissue functions. In this approach, scaffolds provide a temporary mechanical and vascular support for tissue regeneration while tissue in-growth is being formed. These scaffolds must be biocompatible, biodegradable, with appropriate porosity, pore structure and distribution, and optimal vascularization with both surface and structural compatibility. The challenge is to establish a proper balance between porosity and mechanical performance of scaffolds.This work investigates the use of two different types of triple periodic minimal surfaces, Schwarz and Schoen, in order to design better biomimetic scaffolds with high surface-to-volume ratio, high porosity and good mechanical properties. The mechanical behaviour of these structures is assessed through the finite element method software Abaqus. The effect of two parametric parameters (thickness and surface radius) is also evaluated regarding its porosity and mechanical behaviour.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Engineering & Physics - Volume 36, Issue 8, August 2014, Pages 1033–1040
نویسندگان
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