کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8770107 | 1598519 | 2018 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A rare case of isolated castrate resistant bilateral testicular metastases in advanced prostate cancer
ترجمه فارسی عنوان
یک مورد نادر از متاستاز بیضه دو طرفه مقاوم به کاتتر در سرطان پیشرفته پروستات
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کلمات کلیدی
سرطان پروستات مقاوم به کاستراسیون، متاستازها، تومور مفصلی ارکستکتومی،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
چکیده انگلیسی
Testicular metastasis is rare with the prostate being the most common site of primary cancer. We report a case of a 72-year-old man with castration-resistant prostate cancer (CRPC) and known metastases to bone and lymph nodes, who developed bilateral painful swollen testes 3 years after the initial diagnosis of prostate cancer. He had first presented with lower urinary tract symptoms (LUTS) with suspicious findings on digital rectal examination of the prostate, and an elevated serum prostate specific antigen (PSA) level of 129Â ng/mL. Transrectal prostate biopsy revealed Gleason 4Â +Â 5 adenocarcinoma. Radiological staging showed locally advanced prostate cancer with extensive metastases to bone and pelvic and retroperitoneal lymph nodes. He was given hormonal therapy for over 2 years until progression to CRPC. Six months later he developed painful bilateral testicular swellings, and serum markers for testicular germ cell cancer were normal. Bilateral orchiectomy was performed, showing metastatic prostate cancer (Gleason 4Â +Â 5) on histology. One month postoperatively his PSA level dropped to 0.1Â ng/mL from a presurgery level of 6.24Â ng/mL.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Journal of Urology - Volume 5, Issue 2, April 2018, Pages 127-130
Journal: Asian Journal of Urology - Volume 5, Issue 2, April 2018, Pages 127-130
نویسندگان
Jiarui Su, Edwin Jonathan Aslim, Hakan Aydin, Puay Hoon Tan, Henry Sun Sien Ho,