کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8787415 | 1601584 | 2017 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nano drug delivery strategy of 5-fluorouracil for the treatment of colorectal cancer
ترجمه فارسی عنوان
استراتژی تحویل نانو مواد 5-فلوروکوراسیل برای درمان سرطان کولورکتال
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
چکیده انگلیسی
Colorectal cancer (CRC) is the leading cause of cancer-related mortality, annually responsible for around 655,000 deaths worldwide. CRC usually develops very slowly, over a period of 10 to 20 years and typically begin as a non-cancerous polyp that develops on the inner layer of the colon or rectum. However, CRC is curable if detected at an early stage. The current treatment of colorectal cancer primarily depends on surgery, chemotherapy, radiotherapy and targeted therapy. A combination of two or more treatments is often recommended to achieve the best outcome, depending on the stage of cancer development. In this review, we summarized the challenges of using 5-Fluorouracil as chemotherapy to treat colorectal cancer, and discussed the implications of nano drug delivery system for improved therapeutic outcome of 5-Flurouracil.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cancer Research and Practice - Volume 4, Issue 2, June 2017, Pages 45-48
Journal: Journal of Cancer Research and Practice - Volume 4, Issue 2, June 2017, Pages 45-48
نویسندگان
Suriyakala Perumal Chandran, Satheesh Babu Natarajan, Sowmiya Chandraseharan, Masliza Suhaini Binti Mohd Shahimi,