کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8787506 | 1601594 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Management of glioblastoma after recurrence: A changing paradigm
ترجمه فارسی عنوان
مدیریت گلیوبلاستوما پس از عود مجدد: یک پارادایم در حال تغییر است
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
چکیده انگلیسی
Glioblastoma remains the most common primary brain tumor after the age of 40Â years. Maximal safe surgery followed by adjuvant chemoradiotherapy has remained the standard treatment for glioblastoma (GBM). But recurrence is an inevitable event in the natural history of GBM with most patients experiencing it after 6-9Â months of primary treatment. Recurrent GBM poses great challenge to manage with no well-defined management protocols. The challenge starts from differentiating radiation necrosis from true local progression. A fine balance needs to be maintained on improving survival and assuring a better quality of life. Treatment options are limited and ranges from re-excision, re-irradiation, systemic chemotherapy or a combination of these. Re-excision and re-irradiation must be attempted in selected patients and has been shown to improve survival outcomes. To facilitate the management of GBM recurrences, a treatment algorithm is proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Egyptian National Cancer Institute - Volume 28, Issue 4, December 2016, Pages 199-210
Journal: Journal of the Egyptian National Cancer Institute - Volume 28, Issue 4, December 2016, Pages 199-210
نویسندگان
Supriya Mallick, Rony Benson, Abdul Hakim, Goura K. Rath,