کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8789417 | 1601683 | 2018 | 21 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Terapia intraperitoneal paliativa en ascitis maligna refractaria
ترجمه فارسی عنوان
درمان درمانی فیزیولوژیک در معرض آسمیت بدخیم مقاوم است
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کلمات کلیدی
Quality of life - کیفیت زندگیAscitis - آسسیتهAscites - آسیت، آبآوردگی شکمCalidad de vida - اصطلاح کیفیت زندگیSurvival - بقاSupervivencia - بقاIntraperitoneal infusion - تزریق داخل صفاقیCuidados paliativos - مراقبت تسکین دهندهPalliative care - مراقبت تسکینیNeoplasias - نئوپلازی هاNeoplasms - نئوپلاسم
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
چکیده انگلیسی
Conventional treatment of refractory malignant ascites is an oncological challenge since it provides little lasting symptomatic improvement. Intraperitoneal therapy, evaluated mainly through series and case reports, and some clinical trials include the use of radioisotopes, chemotherapy, with and without hyperthermia, immunological and biological therapy and others. It has been studied mainly in ascites from ovarian and gastrointestinal cancer. With variable response rates, and although direct comparison is not possible, the most successfully treatments are hyperthermic intraperitoneal chemotherapy (overall response rate between 85.7% and 100%), and catumaxomab, which compared to paracentesis, demonstrated a puncture-free survival of 46 vs. 11 days (HR 0.254) and a median time to next paracentesis of 77 vs. 13 days (HR 0.169). This had a positive impact on quality of life, which is the main goal in the palliative setting. Research in this field continues looking for more lasting, safe, and cost-effective results.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Colombiana de CancerologÃa - Volume 22, Issue 1, JanuaryâMarch 2018, Pages 18-38
Journal: Revista Colombiana de CancerologÃa - Volume 22, Issue 1, JanuaryâMarch 2018, Pages 18-38
نویسندگان
Mauricio Antonio Castaño Cárcamo, Angélica Viviana Fletcher Prieto,