کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8850354 | 1618760 | 2018 | 30 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Triphenyltin exposition induces spermatic parameter alters of Calomys laucha species
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The present study aims to evaluate the influence of triphenyltin (TPT) exposure on reproductive physiology on Calomys laucha species, since this species inhabits regions susceptible to exposure to this contaminant. Animals exposed to the highest dose (10.0â¯mg/kg) presented signs of severe intoxication in only 7 days of exposure, demonstrating a higher sensitivity of this species to triphenyltin. The 10.0â¯mg TPT/kg dose was analyzed separately for short-term exposure and results suggest that exposure to this dose was severely detrimental to sperm activity. Among the main results obtained in the evaluation of sperm kinetics, a reduction in total motility was observed from the 0.5â¯mg TPT/kg group, accentuated according to the increase in the doses of TPT. In progressive motility, there was a decrease from the dose of 0.5â¯mg TPT/kg and maintained the plateau until the dose of 5.0â¯mg TPT/kg. It was also observed an increase in the distances and velocities average path, rectilinear and curvilinear in doses of 2.5 and 5.0â¯mg/kg. From the flow cytometry, evaluation a decrease in mitochondrial functionality was observed as the dose increased. Increased membrane fluidity was also observed from the 5.0â¯mg TPT/kg dose and the acrosome reaction presented higher values at doses of 0.5 and 5.0â¯mg TPT/kg. We can conclude that TPT causes impairment of the sperm activity, reducing it in individuals exposed in the adult phase.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 211, November 2018, Pages 1176-1182
Journal: Chemosphere - Volume 211, November 2018, Pages 1176-1182
نویسندگان
Tiane Ferreira de Castro, Graciela Quintana Saalfeld, Antonio Sergio Junior, Francine Ferreira Padilha, Klebson Silva Santos, Diego Martins Pires, Jessica Ribeiro Pereira, Carine Dahl Corcini, Elton Pinto Colares,