کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8868864 | 1622538 | 2018 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Modeling and MANOVA studies on toxicity and endocrine potential of packaging materials exposed to different extraction schemes
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
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چکیده انگلیسی
The stability of the linings of packaging that is in contact with the goods stored has been of major concern during decades of the development of packaging materials. In this work, an attempt was undertaken to assess the applicability of using two bioassays (Microtox® and XenoScreen YES/YAS) in estimating the stability of packaging (cans, caps, multilayer material) and the impact of their degradation on the toxicity of some simulated media. The assessment of the impact of packaging storage conditions (temperature, disinfection, preservation, extracting and washing solvents) was planned and performed with i) regression modeling of the experimental effects on the ecotoxicity readings, ii) ANOVA and MANOVA estimation of the experimental conditions as significant factors affecting the toxicity results and iii)Â FTIR analysis of the packages. It is shown that the effects of temperature and extraction solvents could be quantitatively assessed by the agreement between all methods applied. It can be stated that temperature and acidity as well as the alcohol content in the sensitive media have the greatest impact on the toxicity of the extract and thus on the stability of the internal lining and the extractability of xenobiotics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Research - Volume 165, August 2018, Pages 294-305
Journal: Environmental Research - Volume 165, August 2018, Pages 294-305
نویسندگان
Natalia SzczepaÅska, BÅażej KudÅak, Stefan Tsakovski, Galina Yotova, Miroslava Nedyalkova, Vasil Simeonov, Anna DoÅÄga, Jacek NamieÅnik,