کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8883841 | 1625909 | 2018 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Environmentally-realistic concentration of cadmium combined with polyunsaturated fatty acids enriched diets modulated non-specific immunity in rainbow trout
ترجمه فارسی عنوان
غلظت محیطی واقع گرایانه کادمیوم همراه با رژیم های غنی شده با اسیدهای چرب غیر اشباع شده مدیتیشن ایمنی غیر اختصاصی در ماهی قزل آلای رنگین
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کلمات کلیدی
ALAcyclo-oxygenase-2TLRRBAPUFAsFCRSGRCOX 2TGF-b1ACH50EPAMPO - DFOalpha-linolenic acid - اسید آلفا لینولنیکEicosapentaenoic acid - اسید ایکوزاپنتانوئیکdocosahexaenoic acid - اسید داکوزاگزوائونیکLinoleic acid - اسید لینولئیکPolyunsaturated fatty acids - اسید چرب اشباع نشدهTransforming growth factor β1 - تبدیل فاکتور رشد β1Toll-like receptor - تیالآرalternative complement pathway - جایگزین مکمل مسیرDHA - دوکوساهگزائنوئیک اسیدEcotoxicology - سم شناسی زیست شناسیTrace element - عنصر ردیابیRespiratory burst activity - فعالیت های انفجاری تنفسیLYZ - لیزlysozyme - لیزوزیم Immunity - مصونیتmyeloperoxidase - میلوپراکسیداز specific growth rate - نرخ رشد خاصfeed conversion ratio - نسبت تبدیل خوراکCadmium - کادمیم
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم آبزیان
چکیده انگلیسی
Nutrition is crucial to grow healthy fish particularly in a context of pollution, overcrowding and pathogen risks. Nowadays, the search for food components able to improve fish health is increasingly developing. Here, the influence of four dietary polyunsaturated fatty acids (PUFAs) that are alpha-linolenic acid (ALA, 18:3n-3), linoleic acid (LA, 18:2n-6), eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) on the sensitivity of rainbow trout (Oncorhynchus mykiss) juveniles to environmentally realistic cadmium (Cd, 0.3â¯Î¼g/L) concentration was investigated. Fish diets were designed to ensure the specific abundance of one of these individual PUFAs, and were given for a 4-week pre-conditioning period followed by a 6-week Cd exposure period. Focus was put on growth performance and immune responses following a short (24â¯h) and a long-term (6 weeks) Cd exposure. For each experimental condition, some fish were submitted to a bacterial challenge (24â¯h) with Aeromonas salmonicida achromogenes at the end of Cd conditioning period. DHA-enriched diet improved growth performances as compared to LA-enriched diet, but also increased ROS production (after short-term exposure to Cd) that could lead to a higher inflammation status, and some immunity-related genes (at short and long-term exposure). We notably highlighted the fact that even a low, environmentally-realistic concentration, Cd can strongly impact the immune system of rainbow trout, and that specific dietary PUFA enrichment strategies can improve growth performance (DHA-enriched diet), provide protection against oxidative stress (ALA- and EPA-enriched diet) and stimulate non-specific immunity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Aquatic Toxicology - Volume 196, March 2018, Pages 104-116
Journal: Aquatic Toxicology - Volume 196, March 2018, Pages 104-116
نویسندگان
Valérie Cornet, Abderrahim Ouaach, S.N.M. Mandiki, Enora Flamion, Aline Ferain, Mélusine Van Larebeke, Benjamin Lemaire, Felipe E. Reyes López, Lluis Tort, Yvan Larondelle, Patrick Kestemont,