کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8941670 | 1645013 | 2018 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Role of adipokines FGF21, leptin and adiponectin in self-concept of youths with obesity
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Role of adipokines FGF21, leptin and adiponectin in self-concept of youths with obesity Role of adipokines FGF21, leptin and adiponectin in self-concept of youths with obesity](/preview/png/8941670.png)
چکیده انگلیسی
The mechanisms by which obesity increases the risk of psychosocial disorders remain unclear. We aimed at exploring the association between obesity and self-concept in Chinese youths and the role of adipokines. Data for 559 participants (aged 14-28 years) were analyzed. Self-concept was assessed by utilizing the Self-Description Questionnaire II (SDQ-II). Subjects with obesity had higher leptin, FGF21 and lower adiponectin levels (all pâ¯<â¯0.001). They also had lower SDQ-II scores especially in the domains of general school, physical abilities, physical appearance and opposite-sex relations (all pâ¯<â¯0.001). Both elevated FGF21 and leptin were correlated with lower scores in math (pâ¯<â¯0.01), physical abilities (pâ¯<â¯0.01), and opposite-sex relations (pâ¯<â¯0.05), meanwhile FGF21 negatively correlated with the scores in general school and honesty/trustworthiness, and leptin negatively correlated with physical appearance (pâ¯<â¯0.01) but positively with verbal (pâ¯<â¯0.01). In contrast, decreased adiponectin was correlated with poorer physical abilities (pâ¯<â¯0.05), physical appearance (pâ¯<â¯0.05), and parent relations (pâ¯<â¯0.01). Moreover, these associations of leptin, FGF21 and adiponectin with certain domains remained significant after adjustment for BMI and other metabolic confounders. In conclusion, youths with obesity experienced poorly on self-concept, and these associations may be explained in part by adipokines leptin, FGF21 and adiponectin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Neuropsychopharmacology - Volume 28, Issue 8, August 2018, Pages 892-902
Journal: European Neuropsychopharmacology - Volume 28, Issue 8, August 2018, Pages 892-902
نویسندگان
Li Ge, Feng Dan, Qu Xiaoxue, Fu Junling, Wang Yonghui, Li Lianxia, Li Lujiao, Lanwen Han, Issy C. Esangbedo, Mingyao Li, Li Ming, Gao Shan,