Cutaneous fibrohistiocytic/fibroblastic tumours: an update

Fibrohistiocytic tumours are among the most frequently encountered soft tissue tumours of the skin. “Fibrohistiocytic” is a descriptive term for cells that resemble both normal fibroblasts and histiocytes, rather than a true line of differentiation. This review discusses the clinical, histologic and immunohistochemical findings in benign, intermediate and malignant fibrohistiocytic tumours, including prognostic and molecular findings. Pertinent entities in the differential diagnosis, with discriminating features, are also discussed.