Intoxicación aguda por comprimidos de liberación sostenida de carbonato de litio. A propósito de un caso clínico

Acute lithium intoxication with plasma levels above 3 mEq/l can be fatal or result in irreversible neurologic sequelae in almost one third of cases, with persitent cerebellar dysfunction in association with dementia of variable degree, and renal, blood, and liver disturbances. Sustained-release tablets may prolong absorption and delay peak plasma concentrations. In such cases, therefore, it is recommended that drug plasma concentrations be monitored during 48-72 hours post-ingestion.