کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9009916 | 1124090 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antimicrobial activity, toxicity and the isolation of a bioactive compound from plants used to treat sexually transmitted diseases
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
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چکیده انگلیسی
Extracts of six ethnobotanically selected medicinal plants (Anredera cordifolia, Elaeodendron transvaalense, Elephantorrhiza burkei, Senna petersiana, Terminalia sericea and Rauvolfia caffra) used traditionally to treat sexually transmitted diseases (STD's) were investigated for antibacterial activity using the agar dilution method. Of the six collected, Terminalia sericea, Senna petersiana and Anredera cordifolia were also investigated for cytotoxicity. The phytochemical studies on Senna petersiana resulted in the isolation of luteolin, which also showed antimicrobial activity. Only the Senna petersiana extract and luteolin isolated from it were tested for antiviral activity and showed some activity at the highest non-toxic concentration of 24 and 500 μg/ml, respectively. The results of the antimicrobial screening support the ethnomedicinal uses of these plants to some extent.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ethnopharmacology - Volume 96, Issue 3, 15 January 2005, Pages 515-519
Journal: Journal of Ethnopharmacology - Volume 96, Issue 3, 15 January 2005, Pages 515-519
نویسندگان
T.E. Tshikalange, J.J.M. Meyer, A.A. Hussein,