کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9033231 | 1131868 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The validity and utility of geotaxis in young rodents
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Negative geotaxis, an automatic, reliable, stimulus-bound, orientation and movement directionally against gravitational cues, is often used for behavioral assessments of infant rodents. We summarize historical and contemporary analyses and conclude that negative geotaxis does not exist in infant rats. Infant rodents placed on inclined surfaces (ranging from 15° to 70° in most tests) are posturally unstable and their compensatory responses have been misinterpreted as negative geotaxis. In fact, recent findings suggest that if infant rats display a geotaxis, they show positive geotaxis on shallow angles of inclination (e.g., 4° and 8°). There may be utility in assessing postures and motoric responses of infant rats on relatively robust angles of inclination, but these are not tests of negative geotaxis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurotoxicology and Teratology - Volume 27, Issue 4, JulyâAugust 2005, Pages 529-533
Journal: Neurotoxicology and Teratology - Volume 27, Issue 4, JulyâAugust 2005, Pages 529-533
نویسندگان
Benjamin A. Motz, Jeffrey R. Alberts,