کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9033716 | 1132090 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Health effects classification and its role in the derivation of minimal risk levels: Renal effects
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
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چکیده انگلیسی
The Agency for Toxic Substances and Disease Registry (ATSDR) derives minimal risk levels (MRLs) for priority hazardous substances. MRLs are health guidance values intended to serve as screening levels for health assessors to select contaminants of concern and to assess potential health effects at hazardous waste sites and areas affected by unplanned releases. Current MRLs are published in ATSDR toxicological profiles and are listed at the ATSDR website at www.atsdr.cdc.gov. To date, ATSDR has derived 125 inhalation MRLs, 207 oral MRLs, and eight external radiation MRLs; 19 MRLs are based on renal effects. This article reports on endpoints used to derive the MRLs. It also presents the ranking of effects into less serious and serious categories as described in ATSDR's Guidance for Developing Toxicological Profiles.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 42, Issue 2, July 2005, Pages 202-208
Journal: Regulatory Toxicology and Pharmacology - Volume 42, Issue 2, July 2005, Pages 202-208
نویسندگان
C.-H. Selene J. Chou, Hana R. Pohl,