Na+K+-ATPase activity as a biomarker of toxaphene toxicity in Unio tumidus

The microsomal fraction isolated from digestive glands was exposed to 1 × 10−3 M, 1 × 10−5 M and 1 × 10−7 M of toxaphene. The obtained data showed that toxaphene induced a loss of ATPase activity in all used concentrations. The Lineweaver-Burk plots for microsomal Na+K+-ATPase in the presence or the absence of toxaphene as an inhibitor indicated a competitive type of inhibition.