کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9110484 | 1155028 | 2005 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Non-thyroid autoantibodies in autoimmune thyroid disease
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کلمات کلیدی
autoantibodiesRheumatoid arthritis - آرتریتروماتوئیدAddison's disease - بیماری آدیسونCoeliac disease - بیماری سلیاکGraves' disease - بیماری گریوسPrimary biliary cirrhosis - سیروز صفراوی اولیهSystemic lupus erythematosus - لوپوس اریتماتوی سیستمیکMyasthenia gravis - میاستنی گراویسLymphocytic hypophysitis - هیپوفیزیت لنفوسیتیکPernicious anaemia - کم خونی سرطانی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Autoimmune thyroid disease is frequently accompanied by other organ-specific and non-organ-specific diseases, most likely because there is sharing of genetic and possibly environmental susceptibility factors. These associations are well recognized in the autoimmune polyglandular syndromes; autoimmune thyroid disease is one of the three major endocrinopathies in the type 2 syndrome and occurs in around 4% of type 1 patients. This review considers the frequency of disease-specific autoantibodies in patients with thyroid autoimmunity and briefly examines the role of such antibodies in performing screening for the associated conditions. Recommendations are made for using such autoantibody tests in the setting of patients with autoimmune thyroid disorders, and also for the utility of screening for thyroid autoimmunity in patients with pernicious anaemia, Addison's disease, coeliac disease, primary biliary cirrhosis, myasthenia gravis, lymphocytic hypophysitis, systemic lupus erythematosus and rheumatoid arthritis. At present, however, there are no large-scale trials that have shown the cost-benefit ratio of autoantibody screening for autoimmunity screening, and clinicians must use individual judgement combined with heightened awareness to identify who to test.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 19, Issue 1, March 2005, Pages 17-32
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 19, Issue 1, March 2005, Pages 17-32
نویسندگان
Anthony P. (Professor of Medicine),