کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9112223 | 1155736 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Arterial stiffness is associated with diabetic retinopathy in type 2 diabetes
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
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چکیده انگلیسی
The purpose of this study was to investigate the association between arterial stiffness and diabetic retinopathy. The subjects comprised 1004 patients with type 2 diabetes. Pulse-wave velocity (PWV) was used as a marker of arterial stiffness. Clinical characteristics, including PWV and diabetic retinopathy (DR), were investigated in a cross-sectional study. PWV, duration of diabetes, systolic blood pressure and hemoglobin A1c level were all significantly higher in patients with diabetic retinopathy than in individuals without this disorder. The association between brachial-ankle PWV and diabetic retinopathy remained significant after statistical adjustment, with increasing odds ratios (ORs) from the second quartile (OR, 2.09; 95% confidence interval (CI), 1.21-3.61), to the third (OR, 2.80; 95% CI, 1.61-4.86) and fourth (OR, 4.64; 95% CI, 2.54-8.52) quartiles. Diabetic retinopathy was, therefore, associated with arterial stiffness in patients with type 2 diabetes. Our findings also suggested that PWV might be a marker of vascular injury caused by chronic hyperglycemia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 68, Issue 2, May 2005, Pages 162-166
Journal: Diabetes Research and Clinical Practice - Volume 68, Issue 2, May 2005, Pages 162-166
نویسندگان
Osamu Ogawa, Chisa Hayashi, Tomiko Nakaniwa, Yasushi Tanaka, Ryuzo Kawamori,