کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9112223 1155736 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Arterial stiffness is associated with diabetic retinopathy in type 2 diabetes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Arterial stiffness is associated with diabetic retinopathy in type 2 diabetes
چکیده انگلیسی
The purpose of this study was to investigate the association between arterial stiffness and diabetic retinopathy. The subjects comprised 1004 patients with type 2 diabetes. Pulse-wave velocity (PWV) was used as a marker of arterial stiffness. Clinical characteristics, including PWV and diabetic retinopathy (DR), were investigated in a cross-sectional study. PWV, duration of diabetes, systolic blood pressure and hemoglobin A1c level were all significantly higher in patients with diabetic retinopathy than in individuals without this disorder. The association between brachial-ankle PWV and diabetic retinopathy remained significant after statistical adjustment, with increasing odds ratios (ORs) from the second quartile (OR, 2.09; 95% confidence interval (CI), 1.21-3.61), to the third (OR, 2.80; 95% CI, 1.61-4.86) and fourth (OR, 4.64; 95% CI, 2.54-8.52) quartiles. Diabetic retinopathy was, therefore, associated with arterial stiffness in patients with type 2 diabetes. Our findings also suggested that PWV might be a marker of vascular injury caused by chronic hyperglycemia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 68, Issue 2, May 2005, Pages 162-166
نویسندگان
, , , , ,