کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9179140 | 1181312 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Platelets and platelet function testing in children
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Platelets play key roles in hemostasis as well as in the pathogenesis of arterial thrombosis. This review summarizes current knowledge of the physiology of pediatric platelets; similarities and differences with platelets from adults are discussed with regards to platelet characteristics, adhesion, activation and secretion, and aggregation. A number of tests of platelet function are reviewed: aggregometry; PFA-100; flow cytometry; and VerifyNow, as well as a test of global hemostasis, thrombelastography. The applications, advantages and shortcomings of these tests in children are described, including their use for monitoring the effects of antiplatelet drugs, which has been done almost exclusively in adult patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Pediatric Cardiology - Volume 21, Issue 1, December 2005, Pages 63-69
Journal: Progress in Pediatric Cardiology - Volume 21, Issue 1, December 2005, Pages 63-69
نویسندگان
Margaret L. Rand, Stefan Kuhle,